Kenzar Plus Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Losartan K 50 mg, hydrochlorothiazide 12.5 mg

Indications/Uses

HTN for patients in whom combination therapy is appropriate.

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Dosage/Direction for Use

1 tab once daily. If uncontrolled BP after 3 wk, may be increased to a max of 2 tab once daily.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity to other sulfonamide-derived drugs. Patients w/ anuria. Pregnancy.

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Special Precautions

Perform periodic determination of serum electrolytes. Hyperglycemia, diabetic patients. Impaired renal function. Symptomatic hypotension. Lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Abdominal pain, edema/swelling, palpitation, back pain, dizziness, cough, sinusitis, upper resp tract infection, rashes.

Drug Interactions

Losartan: Increased serum K w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K. Blunted antihypertensive effects w/ NSAID indomethacin. Hydrochlorothiazide: Potentiation of orthostatic hypotension w/ alcohol, barbiturates or narcotics. Dosage adjustment of antidiabetic drugs (oral agents & insulin). Additive effect w/ other antihypertensive drug. Possible increased responsiveness of skeletal muscle relaxants. Reduced antihypertensive effects w/ NSAIDs.

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Storage

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Description

View Kenzar Plus description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Angiotensin II Antagonists / Diuretics

ATC Classification

C09DA01 - losartan and diuretics ; Belongs to the class of angiotensin II receptor blockers (ARBs) in combination with diuretics. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Kenzar Plus FC tab

Packing/Price

30's (P525/pack, P17.5/film-coated tab)

Kenzar Plus

losartan + hydrochlorothiazide

Manufacturer:

ACME

Distributor:

Bell-Kenz Pharma

Marketer:

Euro Generics